NCERT Class 11 Biotechnology Chapter 9 Answer English Medium | Introduction to Bioinformatics | NCERT Class 11 Biotechnology Book Chapter 9 Book Questions and Answer Solutions English Medium |

Chapter 9

Introduction to Bioinformatics

Exercises

1. Name the two modalities of analysis following sequencing.

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2. Name any three major types of variants.

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3. What are disease-specific variants termed?

(a) somatic

(b) germline

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4. Which is the preferred tool for transcriptome assembly, in the de novo and genome-guided modalities?

(a) Tophat2

(b) Trinity

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5. What is the difference between BLAT and BLAST?

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6. What came first? Structural Bioinformatics or Genome informatics?

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7. Name any two of the major classes of biological macromolecules.

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8. DNA sequences can be represented by which of the following data format?

(a) FASTQ

(b) FASTA

(c) AB1

(d) All of the above

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9. Can a phylogeny be produced dbhjirectly from a multi-fasta file? Justify your answer.

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10. Which tool can help you visualise variants in a circular manner?

(a) UCSC Genome Browser

(b) CIRCOS

(c) IGV

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11. Which of the following approaches can help one in arriving at a comprehensive understanding of the biology of an organism?

(a) Single assay across multiple individuals.

(b) Multiple orthogonal assays across fewer individuals.

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12. Why do we need to sequence nucleic acids? What can one gain by understanding the sequence of nucleic acide?

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